Annane, D;
Pastores, S. M;
Rochwerg, B;
Arlt, W;
Balk, R. A;
Beishuizen, A;
Briegel, J;
Carcillo, J;
Christ-Crain, M;
Cooper, M. S;
Marik, P. E;
Umberto Meduri, G;
Olsen, K. M;
Rodgers, S;
Russell, J. A;
Van den Berghe, G.
OBJECTIVE: To update the 2008 consensus statements for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in adult and pediatric patients. PARTICIPANTS: A multispecialty task force of 16 international experts in Critical Care Medicine, endocrinology, and guideli...
Adrenal Cortex Hormones/administration & dosage,
Sepsis/drug therapy,
Shock, Septic/drug therapy,
Respiratory Distress Syndrome/drug therapy,
Methylprednisolone/therapeutic use,
Critical Illness,
Adrenal Insufficiency/drug therapy,
Hydrocortisone/administration & dosage,
Methylprednisolone/administration & dosage,
Systemic Inflammatory Response Syndrome/drug therapy
Rhodes, A;
Evans, L. E;
Alhazzani, W;
Levy, M. M;
Antonelli, M;
Ferrer, R;
Kumar, A;
Sevransky, J. E;
Sprung, C. L;
Nunnally, M. E;
Rochwerg, B;
Rubenfeld, G. D;
Angus, D. C;
Annane, D;
Beale, R. J;
Bellinghan, G. J;
Bernard, G. R;
Chiche, J. D;
Coopersmith, C;
De Backer, D. P;
French, C. J;
Fujishima, S;
Gerlach, H;
Hidalgo, J. L;
Hollenberg, S. M;
Jones, A. E;
Karnad, D. R;
Kleinpell, R. M;
Koh, Y;
Lisboa, T. C;
Machado, F. R;
Marini, J. J;
Marshall, J. C;
Mazuski, J. E;
McIntyre, L. A;
McLean, A. S;
Mehta, S;
Moreno, R. P;
Myburgh, J;
Navalesi, P;
Nishida, O;
Osborn, T. M;
Perner, A;
Plunkett, C. M;
Ranieri, M;
Schorr, C. A;
Seckel, M. A;
Seymour, C. W;
Shieh, L;
Shukri, K. A;
Simpson, S. Q;
Singer, M;
Thompson, BT;
Townsend, SR;
Van der Poll, T;
Vincent, J. L;
Wiersinga, W. J;
Zimmerman, J. L;
Dellinger, R. P.
OBJECTIVE: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012". DESIGN: A consensus committee of 55 international experts representing 25 international organizations was convened. Nominal groups were assembled at key international meetings (for t...
Chronic Disease/drug therapy,
Sepsis/drug therapy,
Shock, Septic/drug therapy,
Anti-Bacterial Agents/administration & dosage,
Vasoconstrictor Agents/therapeutic use,
Calcitonin/therapeutic use,
Fluid Therapy/methods,
Nutrition Assessment,
Patient Care Planning,
Renal Replacement Therapy,
Respiration, Artificial
Zhang, Zhongheng;
Smischney, Nathan J;
Zhang, Haibo;
Poucke, Sven Van;
Tsirigotis, Panagiotis;
Rello, Jordi;
Honore, Patrick M;
Kuan, Win Sen;
Ray, Juliet June;
Zhou, Jiancang;
Shang, You;
Yu, Yuetian;
Jung, Christian;
Robba, Chiara;
Taccone, Fabio Silvio;
Caironi, Pietro;
Grimaldi, David;
Hofer, Stefan;
Dimopoulos, George;
Leone, Marc;
Hong, Sang-Bum;
Bahloul, Mabrouk;
Argaud, Laurent;
Kim, Won Young;
Spapen, Herbert D;
Rocco, Jose Rodolfo.
: Sepsis is a heterogeneous disease caused by an infection stimulus that triggers several complex
local and systemic immuno-inflammatory reactions, which results in multiple organ dysfunction and
significant morbidity and mortality. The diagnosis of sepsis is challenging because there is no gold standard...